New developments in SciFinder-n

We would like to recommend our access to SciFinder-n, the new database of American Chemical Society – Chemical Abstracts Service.

SciFinder-n is a research discovery application that provides integrated access to the world’s most comprehensive and authoritative source of references, substances and reactions in chemistry and related sciences.

Below is a summary of enhancements included in the most recent CAS SciFinder-n release.

Reaction detail page display updates

The newly updated user interface on the Reaction Detail page creates better data organization and introduces the concept of reaction transformations, which describes the specific change occurring as a result of the reaction.

Changes to the page include

*Centering the reaction scheme at the top of the page

*Shifting reaction overview and source document information to the left-hand side of the page

*Placing Transformations and Reaction Notes below the Reaction Steps and Experimental Protocols

Additional enhancements

*Sequence Search query normalization – Users can perform sequence searches using a variety of input formats, notably, EMBL, GCG, and GenBank.

*Reaction Search by CAS Reaction Number – Providing another simplified search option, reactions can now be searched using the CAS Reaction Number. Results will be displayed for matching single-step reactions, or multi-step reactions containing the single step identified by the Reaction Number.

*Identification of unmapped reaction results – When performing reaction mapping, a No Mapping Data Available filter is now in place to help distinguish between mapped and unmapped reaction results being reviewed.


The database is available through academic IP addresses and from home with the help of the proxy server.

Individual registration is necessary from academic IP addresses with an USZ-email address. Existing SciFinder registrations also work in the new interface.

You can register at this link.

Quick reference guide: click here.

If you have any problems, please send a message to e-help.

Date: November 28, 2022